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Literature summary for 3.4.24.40 extracted from
- Specificity of Pseudomonas aeruginosa serralysin revisited, using biologically active peptides as substrates (1998), Biochim. Biophys. Acta, 1387, 378-386.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Pseudomonas aeruginosa |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | Zn2+ is bound at the active site | Pseudomonas aeruginosa |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 49500 | - |
commercial preparation, SDS-PAGE | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pseudomonas aeruginosa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| angiotensin I + H2O | - |
Pseudomonas aeruginosa | DRVY + IHPFLHL + DRVYI + HPFHL | - |
? | |
| angiotensin II + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| Fibronectin + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| peptide 6A + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| substance P + H2O | - |
Pseudomonas aeruginosa | RPKPQQFFG + LM-NH2 + RPKPQQFF + GLM-NH2 + RPKQQF + FGLM-NH2 | - |
? | |
| substance P 1-7 + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| substance P 1-9 + H2O | - |
Pseudomonas aeruginosa | RPKP + QQFFG + RPKQQ + FFG | - |
? | |
| substance P 7-11 + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| substance P 8-11 + H2O | - |
Pseudomonas aeruginosa | ? | - |
? | |
| substance P(free acid) + H2O | - |
Pseudomonas aeruginosa | RPKPQQFFG + LM + RPKPQQFF + GLM + RPKQQF + FGLM | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Alkaline protease | - |
Pseudomonas aeruginosa |
| AP | - |
Pseudomonas aeruginosa |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.02 | - |
substance P 8-11 | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 0.038 | - |
peptide 6A | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 0.08 | - |
substance P 7-11 | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 0.53 | - |
angiotensin II | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 1.52 | - |
angiotensin I | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 2.94 | - |
angiotensin I | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 6.08 | - |
angiotensin II | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 33 | - |
substance P 1-7 | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 56 | - |
substance P 1-9 | pH 8.6, 30°C | Pseudomonas aeruginosa | |
| 160 | - |
substance P(free acid) | pH 8.6, 30°C | Pseudomonas aeruginosa | |
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