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Literature summary for 3.4.24.40 extracted from

  • Bae, K.H.; Kim, I.C.; Kim, K.S.; Shin, Y.C.; Byun, S.M.
    The Leu-3 residue of Serratia marcescens metalloprotease inhibitor is important in inhibitory activity and binding with Serratia marcescens metalloprotease (1998), Arch. Biochem. Biophys., 352, 37-43.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
L3A SmaPI mutant inhibitor Serratia marcescens
L3D SmaPI mutant inhibitor Serratia marcescens
L3F SmaPI mutant inhibitor Serratia marcescens
L3G SmaPI mutant inhibitor Serratia marcescens
L3I SmaPI mutant inhibitor Serratia marcescens
L3K SmaPI mutant inhibitor Serratia marcescens
L3P SmaPI mutant inhibitor Serratia marcescens
SmaPI Serratia marcescens metalloprotease inhibitor, wild-type Serratia marcescens
SmaPIAddA mutant inhibitor Serratia marcescens
SmaPIDelG mutant inhibitor Serratia marcescens
SmaPIDelG1-L3 mutant inhibitor Serratia marcescens
SmaPIDelG1-S2 mutant inhibitor Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
azocasein + H2O
-
Serratia marcescens ?
-
?
N-alpha-benzoyl-DL-arginine-p-nitroanilide + H2O artificial substrate BAPNA Serratia marcescens N-alpha-benzoyl-DL-arginine + 4-nitroaniline
-
?

Synonyms

Synonyms Comment Organism
Serratia marcescens metalloprotease
-
Serratia marcescens
SMP
-
Serratia marcescens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000713
-
SmaPI pH 7.0, 25°C, wild-type inhibitor Serratia marcescens
0.000723
-
L3I SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000725
-
SmaPIDelG1 pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000728
-
SmaPIAddA pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000736
-
SmaPIDelG1-S2 pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000791
-
L3F SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000903
-
L3DSmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.000958
-
L3P SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.00107
-
L3G SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.00184
-
L3K SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.00217
-
L3D SmaPI pH 7.0, 25°C, mutant inhibitor Serratia marcescens
0.00274
-
SmaPIDelG1-L3 pH 7.0, 25°C, mutant inhibitor Serratia marcescens