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Literature summary for 3.4.24.13 extracted from

  • Ayala, B.P.; Vasquez, B.; Clary, S.; Tainer, J.A.; Rodland, K.; So, M.
    The pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease (2001), Cell. Microbiol., 3, 265-275.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
LAMP1 + H2O Neisseria gonorrhoeae LAMP1 is a major integral membrane glycoprotein of lysosomes and significantly reduces its steady-state levels in an infected cell. Pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of LAMP1 accessible to IgA1 protease ?
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Organism

Organism UniProt Comment Textmining
Neisseria gonorrhoeae
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
LAMP1 + H2O i.e. lysosome-associated membrane protein 1 Neisseria gonorrhoeae ?
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?
LAMP1 + H2O LAMP1 is a major integral membrane glycoprotein of lysosomes and significantly reduces its steady-state levels in an infected cell. Pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of LAMP1 accessible to IgA1 protease Neisseria gonorrhoeae ?
-
?