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Literature summary for 3.4.22.B29 extracted from
- Down-regulation of calpain 9 is linked to hypertensive heart and kidney disease (2005), Cell. Physiol. Biochem., 15, 109-116.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Rattus norvegicus |  |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | differential regulation of calpain 9 plays a role in hypertensive target organ damage | Rattus norvegicus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calpastatin | - |
Rattus norvegicus | |
| NaCl | 4% down-regulates the enzyme by more than 50% in the kidney and heart but not in the aorta | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | required for activation | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | O35920 | Dahl salt-sensitive rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain 9 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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