Literature summary for 3.4.21.B45 extracted from

Ulbricht, D.; Tindall, C.A.; Oertwig, K.; Hanke, S.; Straeter, N.; Heiker, J.T.
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin (2018), Biol. Chem., 399, 1079-1084 .

Search for more literature for 3.4.21.B45

Inhibitors

Inhibitors	Comment	Organism	Structure
vaspin	vaspin represents a multispecific serpin targeting the kallikrein proteases KLK7 and KLK14	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9P0G3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adipose tissue	-	Homo sapiens	-
pancreas	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
kallikrein-related peptidase 14	-	Homo sapiens
KLK14	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	aberrant enzyme activity is associated with inflammatory skin diseases such as Netherton syndrome but also with various serious forms of cancer	Homo sapiens
physiological function	important protease in skin desquamation	Homo sapiens

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Release 2023.1 (January 2023)