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Literature summary for 3.4.21.78 extracted from
- Selective chemical functional probes of granzymes A and B reveal granzyme B Is a major effector of natural killer cell-mediated lysis of target cells (2005), Chem. Biol., 12, 567-577.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Bio-x-IGN(AmPhg)P-(Oph)2 | specific and irreversible inhibition both in vitro and in cells | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | compared with granzyme B, granzyme A is minor effector of target cell lysis by natural killer cells | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | compared with granzyme B, granzyme A is minor effector of target cell lysis by natural killer cells | Homo sapiens | ? | - |
? | |
| Suc-AAPR-p-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
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