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Information on EC 3.4.21.78 - granzyme A

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.78 granzyme A
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
tsp-1, granzyme a, h factor, gzm a, gzma/k, ctla3, ctl tryptase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: -Arg-/-, -Lys-/- >> -Phe-/- in small molecule substrates
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including fibronectin, type IV collagen and nucleolin. Preferential cleavage:-Arg-+-,-Lys-+- >>-Phe-+- in small molecule substrates, he term-+- depicts the point of cleavage
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