Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
kininogen + H2O | Homo sapiens | - |
kinin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gastrointestinal stromal tumor cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Val-Leu-Arg-4-nitroanilide + H2O | - |
Homo sapiens | D-Val-Leu-Arg + 4-nitroaniline | - |
? | |
kininogen + H2O | - |
Homo sapiens | kinin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HK1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | human tissue kallikrein is produced and released by gastrointestinal stromal tumor and participates in tumor invasion. Human tissue kallikrein released by gastrointestinal stromal tumor cells promotes endothelial cell migration and network formation through kinin-dependent mechanisms | Homo sapiens |