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Literature summary for 3.4.17.24 extracted from

  • Tanco, S.; Tort, O.; Demol, H.; Aviles, F.X.; Gevaert, K.; Van Damme, P.; Lorenzo, J.
    C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini (2015), Mol. Cell. Proteomics, 14, 177-190 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.17.24

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UPW5
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information CCP1 processes both glutamates as well as C-terminal aspartates Homo sapiens ?
-
-
[40S ribosomal protein S9]-KNAKKGQGGAGAGDDEEED + H2O
-
 Homo sapiens [40S ribosomal protein S9]-KNAKKGQGGAGAGDD + Glu-Glu-Glu-Asp
-
 ?
[40S ribosomal protein S9]-KNAKKGQGGAGAGDDEEED + H2O
-
 Homo sapiens [40S ribosomal protein S9]-KNAKKGQGGAGAGDDE + Glu-Glu-Asp
-
 ?
[alpha-tubulin 1A/1B]-EDMAALEKDYEEVGVDSVEGEGEEEGEE + H2O in the case of alpha-tubulin, it is considered that CCP1 uses as substrate the pool of detyrosinated tubulin naturally present in the cell Homo sapiens [alpha-tubulin 1A/1B]-EDMAALEKDYEEVGVDSVEGEGEEEG + Glu-Glu
-
 ?
[alpha-tubulin 1C]-EDMAALEKDYEEVGADSADGEDEGEE + H2O in the case of alpha-tubulin, it is considered that CCP1 uses as substrate the pool of detyrosinated tubulin naturally present in the cell Homo sapiens [alpha-tubulin 1C]-EDMAALEKDYEEVGADSADGEDEG + Glu-Glu
-
 ?
[eukaryotic translation initiation factor 4H]-EEVVQKEQE + H2O
-
 Homo sapiens [eukaryotic translation initiation factor 4H]-EEVVQKEQ + Glu
-
 ?
[high mobility group protein B1]-EEEEDEEDEEDEEEEEDEEDEDEEEDDDDE + H2O
-
 Homo sapiens [high mobility group protein B1] + EEEEDEEDEEDEEEEEDEEDEDEEEDDDDE
-
 ?
[high mobility group protein B2]-EDEEEEEEEEDEDEEEEDEDEE + H2O
-
 Homo sapiens [high mobility group protein B2] + EDEEEEEEEEDEDEEEEDEDEE
-
 ?
[high mobility group protein B3]-KKVEEEDEEEEEEEEEEEEEEDE + H2O
-
 Homo sapiens [high mobility group protein B3]-KKVEEED + EEEEEEEEEEEEEEDE
-
 ?
[high mobility group protein B3]-KKVEEEDEEEEEEEEEEEEEEDE + H2O
-
 Homo sapiens [high mobility group protein B3]-KKVEEEDE + EEEEEEEEEEEEEDE
-
 ?
[myosin light chain kinase 1/telokinc]-EEEEEE + H2O
-
 Homo sapiens [myosin light chain kinase 1/telokinc] + EEEEEE
-
 ?
[stathmin]-KNKESKDPADETEAD + H2O
-
 Homo sapiens [stathmin]-KNKESKDPADETEA + Asp
-
 ?
[TRAF-type zinc finger domain-containing protein]-TAKAKPSKQQGAGDAEEEEEE + H2O
-
 Homo sapiens [TRAF-type zinc finger domain-containing protein]-TAKAKPSKQQGAGDA + Glu-Glu-Glu-Glu-Glu-Glu
-
 ?

Synonyms

Synonyms Comment Organism
CCP1
-
 Homo sapiens
cytosolic carboxypeptidase 1
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
 assay at Homo sapiens

General Information

General Information Comment Organism
physiological function CCP1-mediated shortening of acidic protein tails might regulate protein-protein and protein-DNA interactions Homo sapiens