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Literature summary for 3.4.17.23 extracted from
- Estradiol reduces ACE2 and TMPRSS2 mRNA levels in A549 human lung epithelial cells (2022), Drug Dev. Res., 2022, 1-6 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | 17-beta-estradiol may reduce SARS-CoV-2 infection of lung epithelial cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9BYF1 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| A-549 cell | - |
Homo sapiens | - |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | treatment of A-549 lung epithelial cells with 17-beta-estradiol reduces the cellular mRNA levels of ACE2 and TMPRSS2 mRNA, while not affecting FURIN expression | down |
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Release 2023.1 (January 2023)
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