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Literature summary for 3.4.17.23 extracted from

  • Gutierrez-Chamorro, L.; Riveira-Munoz, E.; Barrios, C.; Palau, V.; Nevot, M.; Pedreno-Lopez, S.; Senserrich, J.; Massanella, M.; Clotet, B.; Cabrera, C.; Mitja, O.; Crespo, M.; Pascual, J.; Riera, M.; Ballana, E.
    SARS-CoV-2 infection modulates ACE2 function and subsequent inflammatory responses in swabs and plasma of COVID-19 patients (2021), Viruses, 13, 1715 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
diagnostics ACE2 levels is a putative early biomarker of SARS-CoV-2 infection severity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BYF1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-
nasopharynx
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
ACE2
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens mechanisms exist by which SARS-CoV-2 induces shedding of ACE2, together with downregulation of ACE2 gene expression down

General Information

General Information Comment Organism
physiological function angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the COVID-19 disease Homo sapiens