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Literature summary for 3.4.17.20 extracted from

  • Bajzar, L.; Manuel, R.; Nesheim, M.E.
    Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor (1995), J. Biol. Chem., 270, 14477-14484.
    View publication on PubMed
Search for more literature for 3.4.17.20

Activating Compound

Activating Compound Comment Organism Structure
thrombin
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
2-Guanidinoethylmercaptosuccinic acid i.e. GEMSA Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
12000
-
 x * 25000 + x * 12000, derived by cleavage at Arg330, inactive form, SDS-PAGE Homo sapiens
25000
-
 x * 25000 + x * 12000, derived by cleavage at Arg330, inactive form, SDS-PAGE Homo sapiens
35000
-
 x * 35000, active enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibrin, partially degraded + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibrin, partially degraded + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 60000-62000, zymogen, SDS-PAGE Homo sapiens
? x * 25000 + x * 12000, derived by cleavage at Arg330, inactive form, SDS-PAGE Homo sapiens
? x * 35000, active enzyme Homo sapiens