Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.17.12 extracted from

  • Tan, F.; Deddish, P.A.; Skidgel, R.A.
    Human carboxypeptidase M (1995), Methods Enzymol., 248, 663-675.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
bradykinin
-
Homo sapiens
0.046
-
Met5-Arg6-enkephalin
-
Homo sapiens
0.063
-
Leu5-Arg6-enkephalin
-
Homo sapiens
0.375
-
Met5-Lys6-enkephalin
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Homo sapiens 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
x * 62000, human, SDS-PAGE with or without reduction Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein carbohydrate content: 23% by weight Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.344
-
-
Homo sapiens

Storage Stability

Storage Stability Organism
-20°C, 50% v/v glycerol, stable for at least 1 year Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-Gly-Arg + H2O
-
Homo sapiens benzoyl-Gly + Arg
-
?
benzoyl-Gly-Lys + H2O
-
Homo sapiens benzoyl-Gly + Lys
-
?
dynorphin A(1-13) + H2O i.e. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys Homo sapiens Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu + Lys
-
?
Leu5-Arg6-enkephalin + H2O
-
Homo sapiens ?
-
?
Met5-Arg6-enkephalin + H2O
-
Homo sapiens ?
-
?
Met5-Lys6-enkephalin + H2O
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
? x * 62000, human, SDS-PAGE with or without reduction Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.77
-
Leu5-Arg6-enkephalin
-
Homo sapiens
2.45
-
bradykinin
-
Homo sapiens
11.1
-
Met5-Lys6-enkephalin
-
Homo sapiens
15.6
-
Met5-Arg6-enkephalin
-
Homo sapiens