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Literature summary for 3.4.13.23 extracted from
- BLH1 codes for a yeast thiol aminopeptidase, the equivalent of mammalian bleomycin hydrolase (1993), J. Biol. Chem., 268, 7036-7043 .
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 220000 | - |
gel filtration | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | Q01532 | - |
- |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme displays broad specificity, cleaving substrate with beta-naphthylamine as chromophore and also the corresponding 4-nitroanilides. Enzyme hydrolyzes aminopeptidase substrates with a neutral or basic amino acid and L-Glu-beta-naphthylamide | Saccharomyces cerevisiae | ? | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 55400, calculated from sequence and SDS-PAGE | Saccharomyces cerevisiae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BLH1 | - |
Saccharomyces cerevisiae |
| lap3 | - |
Saccharomyces cerevisiae |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Saccharomyces cerevisiae | isoelectric focusing | - |
6 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | deletion of the BLHl gene is not lethal under normal growth conditions. blhl mutants show hypersensitivity to bleomycin | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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