Application | Comment | Organism |
---|---|---|
medicine | investigation on the expression and genetic polymorphism of microsomal epoxide hydrolase in non-small cell lung cancer patients. Enzyme is expressed in 83% of biopsies analyzed, and the major allelic expression pattern is fast type (Tyr113) in exon 3 (90.3%) and slow type (His139) in exon 4 (100%). A significant difference in patient survival is found when enzyme expression and adriamycin-containing chemotherapy are used to group patients. With respect to cancer risk and disease progression, the expression level of enzyme seems as important as genetic polymorphism | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P07099 | non-small cell lung cancer patients | - |