Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea | - |
Homo sapiens | |
1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea | - |
Mus musculus | |
1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea | - |
Rattus norvegicus | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid | - |
Homo sapiens | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid | - |
Mus musculus | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid | - |
Rattus norvegicus | |
12-(3-adamantan-1-ylureido)dodecanoic acid | - |
Homo sapiens | |
12-(3-adamantan-1-ylureido)dodecanoic acid | - |
Mus musculus | |
12-(3-adamantan-1-ylureido)dodecanoic acid | - |
Rattus norvegicus | |
12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | - |
Homo sapiens | |
12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | - |
Mus musculus | |
12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | - |
Rattus norvegicus | |
cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | - |
Homo sapiens | |
cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | - |
Mus musculus | |
cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | - |
Rattus norvegicus | |
N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | - |
Homo sapiens | |
N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | - |
Mus musculus | |
N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | - |
Rattus norvegicus | |
trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | potent sEH inhibitor | Homo sapiens | |
trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | potent sEH inhibitor | Mus musculus | |
trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | potent sEH inhibitor | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyano(2-methoxynaphthalen-6-yl)methyl(3-phenyloxiran-2-yl)methyl carbonate + H2O | - |
Rattus norvegicus | ? | - |
? | |
cyano(6-methoxynaphthalen-2-yl)methyl (3-phenyloxiran-2-yl)acetate + H2O | - |
Mus musculus | [1,2-dihydroxy-2-(3-phenyloxiran-2-yl)ethoxy](6-methoxynaphthalen-2-yl)acetonitrile | - |
? | |
cyano(6-methoxynaphthalen-2-yl)methyl (3-phenyloxiran-2-yl)acetate + H2O | - |
Homo sapiens | [1,2-dihydroxy-2-(3-phenyloxiran-2-yl)ethoxy](6-methoxynaphthalen-2-yl)acetonitrile | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SEH | - |
Mus musculus |
SEH | - |
Homo sapiens |
SEH | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000008 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | 12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | |
0.0000009 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.0000013 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.000003 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | 12-(3-adamantan-1-ylureido)dodecanoic acid | |
0.000004 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.000004 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | 12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | |
0.000005 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | 12-(3-adamantan-1-ylureido)dodecanoic acid butyl ester | |
0.000006 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | |
0.000007 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | |
0.000007 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.000008 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.000008 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | trans-4-[4-(3-adamantan-1-yl-ureido)cyclohexyloxy]benzoic acid | |
0.000009 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | N-(1-acetylpiperidin-4-yl)-N'-(adamant-1-yl)urea | |
0.00001 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | 12-(3-adamantan-1-ylureido)dodecanoic acid | |
0.000011 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | 12-(3-adamantan-1-ylureido)dodecanoic acid | |
0.000012 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Homo sapiens | 1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea | |
0.000079 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Rattus norvegicus | 1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea | |
0.000097 | - |
in bis-Tris/HCl buffer, pH 7.0, at 25°C | Mus musculus | 1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl)urea |