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Literature summary for 3.13.2.1 extracted from

  • Li, Q.; Mao, L.; Wang, R.; Zhu, L.; Xue, L.
    Overexpression of S-adenosylhomocysteine hydrolase (SAHH) in esophageal squamous cell carcinoma (ESCC) cell lines: effects on apoptosis, migration and adhesion of cells (2014), Mol. Biol. Rep., 41, 2409-2417.
    View publication on PubMed
Search for more literature for 3.13.2.1

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 x * 48000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-homocysteine + H2O Homo sapiens
-
 L-homocysteine + adenosine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
EC-9706 cell
-
 Homo sapiens
-
Eca-109 cell
-
 Homo sapiens
-
esophageal epithelium
-
 Homo sapiens
-
esophageal squamous cell carcinoma cell
-
 Homo sapiens
-
HET-1A cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-homocysteine + H2O
-
 Homo sapiens L-homocysteine + adenosine
-
 ?

Subunits

Subunits Comment Organism
? x * 48000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
S-adenosylhomocysteine hydrolase
-
 Homo sapiens
SAHH
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme is downregulated in esophageal squamous cell carcinoma cells compared with normal esophageal epithelial cells down

General Information

General Information Comment Organism
physiological function the enzyme can promote apoptosis, inhibit migration and adhesion of esophageal squamous cell carcinoma cells suggesting that it may be involved in carcinogenesis of the esophagus Homo sapiens