Any feedback?
Literature summary for 3.13.2.1 extracted from
- Purification and characterization of S-adenosylhomocysteine hydrolase from mouse mastocytoma P-815 cells. Evidence for cell cycle-specific fluctuation of the enzyme activity (1985), J. Biochem., 97, 189-197.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2'-deoxyadenosine | - |
Mus musculus |  |
| 2-Aminoadenosine | - |
Mus musculus | |
| 2-chloroadenosine | - |
Mus musculus | |
| adenine | - |
Mus musculus | |
| adenosine-5'-monophosphate | poor | Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00029 | - |
adenosine | - |
Mus musculus | |
| 0.00077 | - |
S-adenosyl-L-homocysteine | - |
Mus musculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45000 | - |
probably homotetramer, 4 * 45000, SDS-PAGE | Mus musculus |
| 190000 | - |
gel filtration | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-homocysteine + H2O | Mus musculus | - |
adenosine + L-homocysteine | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 260fold to homogeneity | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| P-815 cell | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Mus musculus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DL-homocysteine + adenosine | - |
Mus musculus | S-adenosyl-DL-homocysteine | - |
r | |
| S-adenosyl-L-homocysteine + H2O | - |
Mus musculus | adenosine + L-homocysteine | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | probably homotetramer, 4 * 45000, SDS-PAGE | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.2 | hydrolysis of S-adenosyl-L-homocysteine | Mus musculus |
| 7.8 | 8 | synthesis of S-adenosyl-L-homocysteine | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
