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Literature summary for 3.13.2.1 extracted from

  • Narayanan, S.R.; Borchardt, R.T.
    Purification of bovine liver S-adenosylhomocysteine hydrolase by affinity chromatography on blue dextran-agarose (1988), Biochim. Biophys. Acta, 965, 22-28.
    View publication on PubMed
Search for more literature for 3.13.2.1

Application

Application Comment Organism
medicine antiviral drug design Bos taurus
medicine chemotherapeutic drug design Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-homocysteine + H2O Bos taurus
-
 adenosine + L-homocysteine
-
 r

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
3250fold to homogeneity Bos taurus

Reaction

Reaction Comment Organism Reaction ID
S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine reaction equilibrium is in vitro strongly in direction of synthesis of S-adenosyl-L-homocysteine Bos taurus
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3
-
-
 Bos taurus

Storage Stability

Storage Stability Organism
-20°C, with 5% glycerol Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-homocysteine + H2O
-
 Bos taurus adenosine + L-homocysteine
-
 r

Subunits

Subunits Comment Organism
tetramer
-
 Bos taurus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Bos taurus