Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sildenafil | - |
Homo sapiens | |
sildenafil | IC50: 7.8 nM | Oryctolagus cuniculus | |
tadalafil | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | PDE5 gene expression and activity are androgen-dependent in vas deferens | ? | - |
? | |
additional information | Oryctolagus cuniculus | PDE5 gene expression and activity are androgen-dependent in vas deferens | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
vas deferens | detected in all different muscular layers, as well as endothelial and smooth muscle cells of the blood vessels. No activity in luminal epithelial cells | Homo sapiens | - |
vas deferens | detected in all different muscular layers, as well as endothelial and smoothmuscle cells of the blood vessels. No activity in luminal epithelial cells | Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PDE5 gene expression and activity are androgen-dependent in vas deferens | Homo sapiens | ? | - |
? | |
additional information | PDE5 gene expression and activity are androgen-dependent in vas deferens | Oryctolagus cuniculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDE5 | - |
Homo sapiens |
PDE5 | - |
Oryctolagus cuniculus |
phosphodiesterase 5 | - |
Homo sapiens |
phosphodiesterase 5 | - |
Oryctolagus cuniculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000078 | - |
IC50: 7.8 nM | Oryctolagus cuniculus | sildenafil |