Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-nonenal | at 1-100 nM: activates PL-C in DMSO-differentiated HL-60 cells, at 1-10 nM: activates PL-C in undifferentiated HL-60 cells | Homo sapiens | |
4-hydroxynonenal | at 10-1000 nM, activates PL-C in both undifferentiated and DMSO-differentiated HL-60 cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HL-60 cell | promyelocytic cell line, undifferentiated and DMSO-differentiated | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | phosphoinositide-specific | Homo sapiens | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PL-C | - |
Homo sapiens |