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Literature summary for 3.1.3.86 extracted from

  • Elong Edimo, W.; Ghosh, S.; Derua, R.; Janssens, V.; Waelkens, E.; Vanderwinden, J.M.; Robe, P.; Erneux, C.
    SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells (2016), J. Cell Sci., 129, 1101-1114 .
    View publication on PubMed
Search for more literature for 3.1.3.86

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O Homo sapiens preferred substrate 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O Homo sapiens
-
 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O15357
-
-

Source Tissue

Source Tissue Comment Organism Textmining
1321-N1 cell
-
 Homo sapiens
-
glioblastoma cell
-
 Homo sapiens
-
LN-229 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O preferred substrate Homo sapiens 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 150000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
INPPL1
-
 Homo sapiens
SHIP2
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme depletion inhibits cell migration of glioblastoma cells Homo sapiens