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Literature summary for 3.1.3.7 extracted from

  • Spiegelberg, B.D.; Xiong, J.P.; Smith, J.J.; Gu, R.F.; York, J.D.
    Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3-nucleotidase inhibited by inositol 1,4-bisphosphate (1999), J. Biol. Chem., 274, 13619-13628.
    View publication on PubMed
Search for more literature for 3.1.3.7

Cloned(Commentary)

Cloned (Comment) Organism
expression in Sf9 cells Homo sapiens
expression in Sf9 cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
inositol 1,4-bisphosphate
-
 Homo sapiens
inositol 1,4-bisphosphate
-
 Mus musculus
Li+
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000475
-
 adenosine 3',5'-bisphosphate native enzyme Mus musculus
0.00052
-
 adenosine 3',5'-bisphosphate recombinant enzyme Mus musculus
0.1
-
 inositol 1,3,4-trisphosphate
-
 Mus musculus
0.113
-
 inositol 1,4-bisphosphate
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens O95861 GenBank AF125042
-
Mus musculus Q9Z0S1 GenBank AF125043
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine 3',5'-bisphosphate + H2O
-
 Mus musculus adenosine 5'-phosphate + phosphate
-
 ?
adenosine 3',5'-bisphosphate + H2O
-
 Homo sapiens adenosine 5'-phosphate + phosphate
-
 ?
inositol 1,3,4-trisphosphate + H2O
-
 Mus musculus inositol 3,4-bisphosphate + phosphate
-
 ?
inositol 1,4-bisphosphate + H2O
-
 Mus musculus inositol 4-phosphate + phosphate
-
 ?