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Literature summary for 3.1.3.53 extracted from
- The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure (2008), J. Cell. Mol. Med., 12, 2158-2164.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| type I cGMP-dependent protein kinase | - |
Homo sapiens |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | congestive heart failure is associated with a decrease in the COOH-terminus leucine zipper and the myosin targeting subunit of MLPC expression | Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 20000 | - |
1 * 20000 + 1 * 38000 + 1 * 110000 | Homo sapiens |
| 38000 | - |
1 * 20000 + 1 * 38000 + 1 * 110000 | Homo sapiens |
| 110000 | - |
1 * 20000 + 1 * 38000 + 1 * 110000 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| smooth muscle | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myosin light-chain phosphate + H2O | 20 kDa myosin light chain | Homo sapiens | myosin light-chain + phosphate | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| trimer | 1 * 20000 + 1 * 38000 + 1 * 110000 | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mLC phosphatase | - |
Homo sapiens |
| MLCP | - |
Homo sapiens |
| myosin light chain phosphatase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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