Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | naturally occuring inhibitors of lysosomal phospholipase A are present in two of the lysosomal-soluble protein fractions obtained in the purification | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Rattus norvegicus | 5764 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Hg2+ | not required | Rattus norvegicus | |
Hg2+ | 2.0 mM, stimulates | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
gel filtration | Rattus norvegicus |
34000 | - |
x * 34000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
one isoenzyme in kidney | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | glycoprotein | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | cortex, only one isoenzyme | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-dioleoylphosphatidylcholine + H2O | - |
Rattus norvegicus | oleic acid + 2-oleoylglycerophosphocholine | - |
? | |
1-palmitoyllysophosphatidylcholine + H2O | weak activity | Rattus norvegicus | palmitic acid + lysophosphatidylcholine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 34000, SDS-PAGE | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
3.6 | 3.8 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
2.6 | 5.2 | pH 2.6: 83% of maximal activity, pH 4.5: 50% of maximal activity, pH 5.2: 10% of maximal activity | Rattus norvegicus |