Cloned (Comment) | Organism |
---|---|
expressed in Trichoplusia ni larvae | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-hydroxyquinoline | specific paraoxonase 1 inhibitor, dose-dependent inhibition | Homo sapiens | |
2-hydroxyquinoline | specific paraoxonase 1 inhibitor, dose-dependent inhibition | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
DEAE-Sepharose column chromatography, Concanavalin A-Sepharose column chromatography, and Sepharose CL-6B gel filtration | Homo sapiens |
DEAE-Sepharose column chromatography, Concanavalin A-Sepharose column chromatography, and Sepharose CL-6B gel filtration | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Homo sapiens | - |
serum | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3.5 | - |
enzyme purified from serum, in 20 mM Tris-HCl buffer (pH 7.4), at 37°C | Homo sapiens |
3.5 | - |
enzyme purified from serum, in 20 mM Tris-HCl buffer (pH 7.4), at 37°C | Oryctolagus cuniculus |
8.5 | - |
recombinant enzyme, after purification, in 20 mM Tris-HCl buffer (pH 7.4), at 37°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Oryctolagus cuniculus | 4-nitrophenol + acetate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 40000-45000, paraoxonase 1 is separated as three bands with an approximate molecular weight of 40000-45000 Da, SDS-PAGE | Homo sapiens |
? | x * 40000-45000, paraoxonase 1 is separated as three bands with an approximate molecular weight of 40000-45000 Da, SDS-PAGE | Oryctolagus cuniculus |