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Literature summary for 3.1.1.118 extracted from

  • Higgs, H.N.; Glomset, J.A.
    Identification of a phosphatidic acid-preferring phospholipase A1 from bovine brain and testis (1994), Proc. Natl. Acad. Sci. USA, 91, 9574-9578 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Bos taurus O46606
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Bos taurus
-
testis
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dioleoyl-3-phosphatidylcholine + H2O
-
Bos taurus 2-oleoyl-3-phosphatidylcholine + oleate
-
?
1,2-dioleoyl-3-phosphatidylethanolamine + H2O
-
Bos taurus 2-oleoyl-3-phosphatidylethanolamine + oleate
-
?
1,2-dioleoyl-3-phosphatidylserine + H2O
-
Bos taurus 2-oleoyl-3-phosphatidylserine + oleate
-
?
1-stearoyl-2-arachidonoyl-sn-phosphatidic acid + H2O
-
Bos taurus 2-arachidonoyl-sn-phosphatidic acid + stearate
-
?
1-stearoyl-2-arachidonoyl-sn-phosphatidylcholine + H2O
-
Bos taurus 2-arachidonoyl-sn-phosphatidylcholine + stearate
-
?
1-stearoyl-2-arachidonoyl-sn-phosphatidylinositol + H2O
-
Bos taurus 2-arachidonoyl-sn-phosphatidylinositol + stearate
-
?
additional information the enzyme hydrolyzes phosphatidic acid 5fold faster than phosphatidylcholine and 3fold faster than phosphatidylinositol Bos taurus ?
-
-

Synonyms

Synonyms Comment Organism
PA-PLA1
-
Bos taurus
phosphatidic acid-preferring phospholipase A1
-
Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8.5
-
Bos taurus

Expression

Organism Comment Expression
Bos taurus the activity of the enzyme in mature bovine testis is more than 10fold higher than that in newborn calf testis up

General Information

General Information Comment Organism
physiological function the enzyme plays a regulatory role in spermatogenesis or sperm function Bos taurus