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Literature summary for 3.1.1.118 extracted from

  • Raimondo, S.; Cristaldi, M.; Fontana, S.; Saieva, L.; Monteleone, F.; Calabrese, G.; Giavaresi, G.; Parenti, R.; Alessandro, R.
    The phospholipase DDHD1 as a new target in colorectal cancer therapy (2018), J. Exp. Clin. Cancer Res., 37, 82 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.118

Application

Application Comment Organism
medicine the enzyme is a target in colorectal cancer therapy Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NEL9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colorectal cancer cell
-
 Homo sapiens
-
HCT-116 cell
-
 Homo sapiens
-
SW-480 cell
-
 Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
DDHD domain-containing protein 1
-
 Homo sapiens
DDHD1
-
 Homo sapiens
PA-PLA1
-
 Homo sapiens
phosphatidic acid-preferring phospholipase A1
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme downregulation reduces in vitro colon cancer cell viability and increases apoptosis rate, without affecting normal cells Homo sapiens
physiological function the enzyme supports colon cancer cell proliferation and survival Homo sapiens