Inhibitors | Comment | Organism | Structure |
---|---|---|---|
HS-CoM | the unmethylated coenzyme M is a reversible competitive inhibitor | Methanothermobacter marburgensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CH3-S-CoM + HS-CoB | Methanothermobacter marburgensis | key step in the convertion of C1 substrates or acetate to methane thereby providing energy for the cell | CoM-S-S-CoB + methane | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanothermobacter marburgensis | - |
isozyme MCR I | - |
Purification (Comment) | Organism |
---|---|
active native isozyme MCR I in presence of HS-CoM | Methanothermobacter marburgensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CH3-S-CoM + HS-CoB | key step in the convertion of C1 substrates or acetate to methane thereby providing energy for the cell | Methanothermobacter marburgensis | CoM-S-S-CoB + methane | - |
? | |
CH3-S-CoM + HS-CoB | the active enzyme is in the MCRred1c form, coordinated ligands of the two paramagnetic MCRred2 states, reduction and oxidation states and critical bond activation step, detailed overview | Methanothermobacter marburgensis | CoM-S-S-CoB + methane | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MCR | - |
Methanothermobacter marburgensis |
methyl-coenzyme M reductase | - |
Methanothermobacter marburgensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
F-430 | active in Ni(I) oxidation state, inactive in Ni(II) state, binding structure and oxidation states, hyperfine interactions of protons, detailed overview | Methanothermobacter marburgensis |