Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.9 extracted from

  • Zhu, X.; Veronese, M.E.; Iocco, P.; McMannus, M.E.
    cDNA cloning and expression of a new form of human aryl sulfotransferase (1996), Int. J. Biochem. Cell Biol., 28, 565-571.
    View publication on PubMed
Search for more literature for 2.8.2.9

Cloned(Commentary)

Cloned (Comment) Organism
HAST4 Homo sapiens
HAST4v, variant of HAST4 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
2,6-Dichloro-4-nitrophenol 50% inhibition of HAST4 at 0.005 mM; 50% inhibition of HAST4v at 0.02 mM Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000203
-
 3'-phosphoadenylylsulfate isoenzyme HAST4v Homo sapiens
0.00525
-
 3'-phosphoadenylylsulfate isoenzyme HAST4 Homo sapiens
0.00775
-
 4-nitrophenol isoenzyme HAST4v Homo sapiens
0.0737
-
 4-nitrophenol isoenzyme HAST4 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P50226
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 4-nitrophenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
additional information no substrate for isozymes HAST4 and HAST4v: dopamine Homo sapiens ?
-
 ?