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Literature summary for 2.8.2.9 extracted from

  • Guo, W.X.; Yang, Y.S.; Chen, X.; McPhie, P.; Jakoby, W.B.
    Changes in substrate specificity of the recombinant form of phenol sulfotransferase IV (tyrosine-ester sulfotransferase) (1994), Chem. Biol. Interact., 92, 25-31.
    View publication on PubMed
Search for more literature for 2.8.2.9

Cloned(Commentary)

Cloned (Comment) Organism
-
 Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
G208R same pattern of specific activities as wild-type enzyme Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00085
-
 quercetin pH 7, 25°C Rattus norvegicus
0.0021
-
 estrone pH 9, 25°C Rattus norvegicus
0.012
-
 hydrocortisone pH 7, 25°C Rattus norvegicus
0.072
-
 4-nitrophenol pH 7, 25°C Rattus norvegicus
0.12
-
 2-naphthol pH 7, 25°C Rattus norvegicus
0.37
-
 2-naphthol pH 5.5, 25°C Rattus norvegicus
0.41
-
 dopamine pH 9, 25°C Rattus norvegicus
0.62
-
 tyrosine methylester pH 8, 25°C Rattus norvegicus
0.78
-
 4-nitrophenol pH 5.5, 25°C Rattus norvegicus
1.1
-
 2-Naphthylamine pH 9, 25°C Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 2-naphthol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
 ?
3'-phosphoadenylylsulfate + 2-naphthylamine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthylamine sulfate
-
 ?
3'-phosphoadenylylsulfate + 4-nitrophenol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
3'-phosphoadenylylsulfate + dopamine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + estrone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + hydrocortisone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + L-tyrosine methyl ester
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate
-
 ?
3'-phosphoadenylylsulfate + quercetin
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
additional information natural enzyme acts best with naphthylamine at an acidic pH and the recombinant enzyme best at high pH values Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
 natural enzyme acts best with naphthylamine at an acidic pH and the recombinant enzyme best at high pH values Rattus norvegicus