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Literature summary for 2.8.2.4 extracted from

  • Sun, M.; Leyh, T.S.
    The human estrogen sulfotransferase: a half-site reactive enzyme (2010), Biochemistry, 49, 4779-4785.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.4

Inhibitors

Inhibitors Comment Organism Structure
17beta-estradiol 17beta-estradiol is a partial kcat-inhibitor (saturation with inhibitor decreases kcat about 7fold without altering Km for PAPS) Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000005
-
 3'-phosphoadenylyl sulfate pH and temperature not specified in the publication Homo sapiens
0.000059
-
 17beta-estradiol pH and temperature not specified in the publication Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol Homo sapiens
-
 adenosine 3',5'-bisphosphate + ?
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 r

Subunits

Subunits Comment Organism
dimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
EST
-
 Homo sapiens
estrogen sulfotransferase
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00008
-
 17beta-estradiol pH and temperature not specified in the publication Homo sapiens