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Literature summary for 2.8.2.4 extracted from

  • Adams, J.B.; Ellyard, R.K.
    Enzymic synthesis of steroid sulphates. VIII. Inhibition of estrogen sulphotransferase by retinoic acid and free fatty acids (1972), Biochim. Biophys. Acta, 260, 724-730.
    View publication on PubMed
Search for more literature for 2.8.2.4

Inhibitors

Inhibitors Comment Organism Structure
3'-AMP
-
 Bos taurus
adenosine 5'-phosphosulfate
-
 Bos taurus
adenosine 5'-sulfate
-
 Bos taurus
cetyltrimethylammonium bromide
-
 Bos taurus
fatty acid unsaturated fatty acid of chain length C11-C14 Bos taurus
myristate inhibition is non-competitive with respect to the substrate estrone Bos taurus
retinoic acid
-
 Bos taurus
Sodium dodecyl sulfate
-
 Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0027
-
 estrone pH 7.5, 37°C Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + estrone Bos taurus
-
 adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 bovine
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + estrone
-
 Bos taurus adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.49
-
 adenosine 5'-phosphosulfate pH 7.5, 37°C Bos taurus
3.37
-
 3'-AMP pH 7.5, 37°C Bos taurus
5
-
 3'-AMP pH 7.5, 37°C Bos taurus
5
-
 adenosine 5'-sulfate pH 7.5, 37°C Bos taurus