Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine 3',5'-bisphosphate | potent, competitive inhibition | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl 5'-phosphosulfate + dehydroepiandrosterone | Rattus norvegicus | - |
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000006 | - |
male rat liver cytosol, substrate 7-hydroxymethyl-12-methylbenz[a]anthracene | Rattus norvegicus |
0.00002 | - |
female rat liver cytosol, substrate 7-hydroxymethyl-12-methylbenz[a]anthracene | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl 5'-phosphosulfate + 7-hydroxymethyl-12-methylbenz[a]anthracene | bioactivation to an electrophilic sulfuric acid ester metabolite | Rattus norvegicus | adenosine 3',5'-bisphosphate + ? | - |
? | |
3'-phosphoadenylyl 5'-phosphosulfate + dehydroepiandrosterone | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
3'-phosphoadenylyl 5'-phosphosulfate + dehydroepiandrosterone | i.e. androst-5-ene-3beta-ol-17-one | Rattus norvegicus | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BAST I | - |
Rattus norvegicus |
bile acid sulfotransferase I | - |
Rattus norvegicus |
hydroxysteroid/bile acid sulfotransferase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Rattus norvegicus |