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Information on EC 2.8.2.34 - glycochenodeoxycholate sulfotransferase

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IUBMB Comments
The enzyme specifically sulfates glycochenodeoxycholate at the 7alpha-position (see also EC 2.8.2.14 bile-salt sulfotransferase). The monohydroxy bile acids glycolithocholate, chenodeoxycholate and ursodeoxycholate act as inhibitors.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
bile acid sulfotransferase, bile acid:3'phosphoadenosine-5'phosphosulfate:sulfotransferase, hydroxysteroid/bile acid sulfotransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3'-phosphoadenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate
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