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Literature summary for 2.8.2.23 extracted from
- The effect of precursor structures on the action of glucosaminyl 3-O-sulfotransferase-1 and the biosynthesis of anticoagulant heparan sulfate (2001), J. Biol. Chem., 276, 28806-28813.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in CHO cells | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | 2-O-sulfation blocks the action of the enzyme at glucosamine residues located to the reducing side of IdoUA units | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phosphoadenylylsulfate + heparan sulfate | enzyme generates sequences containing 6-sulfo-GlcUA-GlcN and 6-sulfo-GlcUA-GlcN | Mus musculus | adenosine 3',5'-bisphosphate + ? | - |
? |  |
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Release 2023.1 (January 2023)
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