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Literature summary for 2.8.2.11 extracted from

  • Roeske-Nielsen, A.; Buschard, K.; Manson, J.; Rastam, L.; Lindblad, U.
    A variation in the cerebroside sulfotransferase gene is linked to exercise-modified insulin resistance and to type 2 diabetes (2009), Exp. Diabetes Res., 2009, 429593.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.11

Application

Application Comment Organism
medicine heterozygosity at SNP rs2267161 in the gene encoding cerebroside sulfotransferase confers increased risk of type 2 diabetes, females with the CC allele show lower insulin resistance Homo sapiens

Protein Variants

Protein Variants Comment Organism
rs2267161 single nucleotide polymorphism located in an exon in the gene encoding CST, heterozygosity confers increased risk of type 2 diabetes Homo sapiens
rs42929 single nucleotide polymorphism located in an intron in the gene encoding CST Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the final step in synthesis of the glycosphingolipid beta-galactosylceramide-3-O-sulfate is performed by cerebroside sulfotransferase ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas the glycosphingolipid beta-galactosylceramide-3-O-sulfate is present in the secretory granules of the insulin producing beta-cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the final step in synthesis of the glycosphingolipid beta-galactosylceramide-3-O-sulfate is performed by cerebroside sulfotransferase Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
cerebroside sulfotransferase
-
 Homo sapiens
CST
-
 Homo sapiens