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Literature summary for 2.8.1.2 extracted from
- Effect of S-allyl-L-cysteine on MCF-7 cell line 3-mercaptopyruvate sulfurtransferase/sulfane sulfur system, viability and apoptosis (2020), Int. J. Mol. Sci., 21, 1090 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | after 24 h and 48 h incubation of MCF-7 cells with 2245 microM S-allyl-L-cysteine, induction of late apoptosis is observed. A decrease in cell viability is observed with increasing S-allyl-L-cysteine concentration and incubation time. S-allyl-L-cysteine has no significant cytotoxic effect on the MCF-7 cells upon all analyzed concentrations | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| S-allyl-L-cysteine | significant decrease in MPST activity at 2245 microM after 24 h and 48 h incubation vs. 1000 microM is associated with decrease in sulfane sulfur levels | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P25325 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MPST | - |
Homo sapiens |
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