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Literature summary for 2.7.8.27 extracted from
- Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast (2006), FEMS Yeast Res., 6, 751-762.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in yeast cells | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | SMS1 not only suppresses the effects of Bax overexpression, but it also blocks the deleterious effects of a number of other stresses, including hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sphingomyelin synthase 1 likely prevents cell death by counteracting stress-mediated accumulation of endogenous sphingolipids | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q8VCQ6 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | SMS1 not only suppresses the effects of Bax overexpression, but it also blocks the deleterious effects of a number of other stresses, including hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sphingomyelin synthase 1 likely prevents cell death by counteracting stress-mediated accumulation of endogenous sphingolipids | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SMS1 | - |
Mus musculus |
| sphingomyelin synthase 1 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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