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Literature summary for 2.7.8.2 extracted from
- Acyl chain length dependency of diacylglycerol cholinephosphotransferase and diacylglycerol ethanolaminephosphotransferase. Effect of different saturated fatty acids at the C-1 or C-2 position of diacylglycerol on solubilized rat liver microsomal enzymes (1978), J. Biol. Chem., 253, 5056-5060.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus | |
| 0.104 | - |
1-myristoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus |  |
| 0.109 | - |
1-pentadecanoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.116 | - |
1-palmitoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.12 | - |
1,2-dioleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.122 | - |
1-tridecanoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.125 | 0.126 | 1-stearoyl-2-oleoyl-sn-glycerol | pH 8.0, 30°C | Rattus norvegicus | |
| 0.133 | - |
1-lauroyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.16 | - |
1-arachidoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.17 | - |
1-heptadecanoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
| 0.21 | - |
1-nonadecanoyl-2-oleoyl-sn-glycerol | 30°C, pH 8.0 | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + 1,2-diacylglycerol | - |
Rattus norvegicus | CMP + a phosphatidylcholine | - |
? | |
| CDP-choline + 1,2-dioleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1,2-dioleoyl-sn-glycero-3-phosphocholine | - |
? | |
| CDP-choline + 1-arachidoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-arachidoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-heptadecanoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-heptadecanoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-lauroyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-lauroyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-myristoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-myristoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-nonadecanoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-nonadecanoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-palmitoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-palmitoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-pentadecanoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-pentadecanoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-stearoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-stearoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| CDP-choline + 1-tridecanoyl-2-oleoyl-sn-glycerol | - |
Rattus norvegicus | CMP + 1-tridecanoyl-2-oleoyl-sn-glycerophosphocholine | - |
? | |
| additional information | specificity overview | Rattus norvegicus | ? | - |
? | |
| additional information | influence of saturated fatty acids on the enzyme activities depends on their location at the C-1 or C-2 position of glycerol | Rattus norvegicus | ? | - |
? | |
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