Any feedback?
Literature summary for 2.7.7.8 extracted from
- Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli (2017), BMC Microbiol., 17, 81 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | polynucleotide phosphorylase enhances both homologous recombination upon P1 transduction and error prone DNA repair of double strand breaks induced by radiomimetic zeocin. Homologous recombination does not require polynucleotide phosphorylasephosphorolytic activity and is modulated by its RNA binding domains whereas error prone DNA repair of zeocin-induced DNA damage is dependent on polynucleotide phosphorylase catalytic activity and cannot be suppressed by overexpression of RNase II. Polynucleotide phosphorylase mutants are more sensitive than the wild-type to zeocin. This phenotype depends on polynucleotide phosphorylasephosphorolytic activity and is suppressed by RNase II | Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
