Cloned (Comment) | Organism |
---|---|
transfection of NIH-3T3 and EPC cells | Danio rerio |
Protein Variants | Comment | Organism |
---|---|---|
additional information | presence of four basic clusters BC1-BC4 in the protein sequence. Deletion of BC3 does not impair nuclear import of isoform Cmas1, deletion of BC1 or BC2, individually or in combination, entail retention in the cytoplasm. neither the deletion of BC1 nor BC2 alters enzymatic activity | Danio rerio |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Danio rerio | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
48200 | - |
or pentamer, 4 * 48200, calculated | Danio rerio |
48200 | - |
or tetramer, 5 * 48200, calculated | Danio rerio |
49600 | - |
4 * 49600, calculated | Danio rerio |
193400 | - |
gel filtration | Danio rerio |
236100 | - |
gel filtration | Danio rerio |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | H9BFW7 | isoform Cmas2 | - |
Danio rerio | Q0E671 | isoform Cmas1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | during the pharyngula stage, expression is restricted to the brain | Danio rerio | - |
central nervous system | robust expression in the entire central nervous system, the somites, the notochord, and the developing pronephric duct | Danio rerio | - |
gastrula | more or less ubiquitously expressed from the end of gastrula through segmentation | Danio rerio | - |
additional information | not detected in skeletal muscle, liver, or kidney | Danio rerio | - |
notochord | robust expression in the entire central nervous system, the somites, the notochord, and the developing pronephric duct | Danio rerio | - |
somite | robust expression in the entire central nervous system, the somites, the notochord, and the developing pronephric duct | Danio rerio | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.2 | - |
substrate N-glycolylneuraminate, pH 7.5, temperature not specified in the publication | Danio rerio |
0.3 | - |
substrate 5-deaminoneuraminate, pH 7.5, temperature not specified in the publication | Danio rerio |
2.7 | - |
substrate N-glycolylneuraminate, pH 7.5, temperature not specified in the publication | Danio rerio |
3.3 | - |
substrate 5-deaminoneuraminate, pH 7.5, temperature not specified in the publication | Danio rerio |
4.5 | - |
substrate N-acetylneuraminate, pH 7.5, temperature not specified in the publication | Danio rerio |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + 5-deaminoneuraminate | - |
Danio rerio | diphosphate + CMP-5-deaminoneuraminate | - |
? | |
CTP + N-acetyl-neuraminate | - |
Danio rerio | diphosphate + CMP-N-acetylneuraminate | - |
? | |
CTP + N-glycolylneuraminate | - |
Danio rerio | diphosphate + CMP-N-glycolylneuraminate | - |
? | |
additional information | enzyme is strictly dependent on CTP | Danio rerio | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
pentamer | or tetramer, 5 * 48200, calculated | Danio rerio |
tetramer | 4 * 49600, calculated | Danio rerio |
tetramer | or pentamer, 4 * 48200, calculated | Danio rerio |
Synonyms | Comment | Organism |
---|---|---|
Cmas1 | - |
Danio rerio |
Cmas2 | - |
Danio rerio |