Cloned (Comment) | Organism |
---|---|
- |
Salmonella enterica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CDPglucose | product inhibition, competitive with respect to CTP, kinetics | Salmonella enterica | |
diphosphate | product inhibition, kinetics | Salmonella enterica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.11 | - |
CTP | pH 8, 37°C | Salmonella enterica | |
0.28 | - |
CTP | pH 8, 37°C | Salmonella enterica | |
0.64 | - |
alpha-D-glucose 1-phosphate | pH 8, 37°C | Salmonella enterica | |
1.89 | - |
diphosphate | pH 8, 37°C | Salmonella enterica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
29035 | - |
x * 29035, calculated from amino acid composition deduced from nucleotide sequence, x * 31000, SDS-PAGE | Salmonella enterica |
31000 | - |
x * 29035, calculated from amino acid composition deduced from nucleotide sequence, x * 31000, SDS-PAGE | Salmonella enterica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + D-glucose 1-phosphate | Salmonella enterica | first of five enzymes committed to CDP-D-abequose biosynthesis | ? | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica | - |
LT2, ecombinant, overproducing strain P9254 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
10.3 | - |
- |
Salmonella enterica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + alpha-D-glucose 1-phosphate | best substrates | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrates in the reverse reaction: ADPglucose, dTDPglucose, UDPglucose | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrate in the forward reaction: alpha-D-mannose 1-phosphate, N-acetyl-alpha-D-glucosamine 1-phosphate | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrate in the forward reaction: dTTP, alpha-D-galactose 1-phosphate | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrate in the forward reaction: ATP, GTP | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | catalyzes bimolecular group transfer reaction | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrates in the reverse reaction: UDPgalactose, UDP-D-mannose, UDP-N-acetyl-D-glucosamine, dTDP-L-rhamnose | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-glucose 1-phosphate | no substrate in the forward reaction: D-ribose 1-phosphate | Salmonella enterica | diphosphate + CDPglucose | - |
r | |
CTP + alpha-D-xylose 1-phosphate | poor substrate | Salmonella enterica | diphosphate + CDPxylose | - |
? | |
CTP + D-glucosamine 1-phosphate | reaction at about 15% the rate with glucose 1-phosphate | Salmonella enterica | diphosphate + CDPglucosamine | - |
? | |
CTP + D-glucose 1-phosphate | first of five enzymes committed to CDP-D-abequose biosynthesis | Salmonella enterica | ? | - |
r | |
UTP + alpha-D-glucose 1-phosphate | poor substrate | Salmonella enterica | diphosphate + UDP-glucose | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 29035, calculated from amino acid composition deduced from nucleotide sequence, x * 31000, SDS-PAGE | Salmonella enterica |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Salmonella enterica |