Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | at 5 mM: reduction in molecular weight from approximately 53000 Da to 17000 Da. This low molecular weight form is partially active in the presence of 2-mercaptoethanol. In absence of 2-mercaptoethanol the low molecular weight form is inactive. At 50 mM: full reactivation of the CMP(ATP) kinase activity followed by dCMP(ATP) and CMP(dCTP) | Rattus norvegicus | |
thioredoxin | activates | Rattus norvegicus |
General Stability | Organism |
---|---|
the enzyme is unstable when fully activated, anions promoting hydrophobic interactions stabilize the active conformation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetamide | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |