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Literature summary for 2.7.13.3 extracted from

  • Boehmer, I.; Spadinger, A.; Ebel, F.
    Functional comparison of the group III hybrid histidine kinases TcsC of Aspergillus fumigatus and NikA of Aspergillus nidulans (2020), Med. Mycol., 58, 362-371 .
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
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Aspergillus fumigatus AfS35
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Aspergillus nidulans Q5B4Q1
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Aspergillus nidulans FGSC A4 Q5B4Q1
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Synonyms

Synonyms Comment Organism
AN4479.2
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 Aspergillus nidulans
NikA
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 Aspergillus nidulans
TcsC
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 Aspergillus fumigatus

General Information

General Information Comment Organism
physiological function isoform NikA is required for wild-type-like growth on Czapek-Dox medium and a normal resistance to certain oxidative stressors. A NikA mutant grows well in the presence of 1 microg/ml fludioxonil, whereas the wild-type strain is severely impaired in growth. In the presence of fludioxonil, the NikA mutant forms fluffy and often white colonies. Resting conidia of the NikA mutant retain their viability during storage at 4°C Aspergillus nidulans
physiological function TcsC is required for wild-type-like growth on Czapek-Dox medium and a normal resistance to certain oxidative stressors. An increased resistance to the cell wall disturbing agents Congo red and Calcofluor white is found for the TcsC mutant Aspergillus fumigatus