Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | light signals activate the MAP kinase via phosphorylation through MAP kinase kinase | Arabidopsis thaliana |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MAP kinase | Arabidopsis thaliana | activation of MAP kinase | ADP + phosphorylated MAP kinase | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | O80396 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
seedling | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MAP kinase | activation of MAP kinase | Arabidopsis thaliana | ADP + phosphorylated MAP kinase | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAPKK3 | - |
Arabidopsis thaliana |
mitogen-activated protein kinase kinase 3 | - |
Arabidopsis thaliana |
MKK3 | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | an mkk3 mutant shows both a hypersensitive response in plant hormone gibberellin and a less sensitive response in red light signaling. Light-induced MAPK activation in wild-type seedlings and constitutive MAPK phosphorylation in dark-grown mkk3 mutant seedlings are found, respectively. The mkk3-1 mutant displays a gibberellic acid-hypersensitive phenotype in hypocotyl elongation, with an additiona long petiole phenotype | Arabidopsis thaliana |
metabolism | the mitogen-activated protein kinase (MAPK) cascade usually functions as an important signaling network involved in physiological and developmental processes in eukaryotes. The MAPK cascade is usually composed of sequential activations of three classes of Ser/Thr protein kinases: MAPK (MPK), MAPK kinase (MKK), and MAPK kinase kinase (MKKK). The MAPK kinase (MKK) gene family has relatively few members in canonical MAPK cascade gene families, which are classified into four groups (A to D) based on the sequence similarities | Arabidopsis thaliana |
physiological function | MKK3 acts in negative regulation in darkness and in light-induced MAPK activation during darklight transition | Arabidopsis thaliana |