Literature summary for 2.7.11.30 extracted from

Liu, J.; Cao, D.; Liu, Y.; Li, Z.; Si, Y.; Wang, Z.; Zhang, Q.; Yu, H.; Wang, X.
Expression and functional analysis of receptor-interacting serine/threonine kinase 2 (RIP2) in Japanese flounder (Paralichthys olivaceus) (2018), Fish Shellfish Immunol., 75, 327-335 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Paralichthys olivaceus	5737	-

Organism

Organism	UniProt	Comment	Textmining
Paralichthys olivaceus	-	Japanese flounder	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Paralichthys olivaceus	-
FG-9307 cell	-	Paralichthys olivaceus	-
gill	-	Paralichthys olivaceus	-
head kidney	high expression	Paralichthys olivaceus	-
heart	weak expression	Paralichthys olivaceus	-
intestine	-	Paralichthys olivaceus	-
liver	-	Paralichthys olivaceus	-
liver	weak expression	Paralichthys olivaceus	-
muscle	weakest expression	Paralichthys olivaceus	-
spleen	highest expression	Paralichthys olivaceus	-

Subunits

Subunits	Comment	Organism
?	x * 66100, calculated from amino acid sequence	Paralichthys olivaceus

Synonyms

Synonyms	Comment	Organism
CARD3	-	Paralichthys olivaceus
CARDIAK	-	Paralichthys olivaceus
CCK	-	Paralichthys olivaceus
receptor-interacting serine/threonine kinase 2	-	Paralichthys olivaceus
RICK	-	Paralichthys olivaceus
RIP2	-	Paralichthys olivaceus
RIPK2	-	Paralichthys olivaceus

pI Value

Organism	Comment	pI Value Maximum	pI Value
Paralichthys olivaceus	calculated from amino acid sequence	-	6.1

Expression

Organism	Comment	Expression
Paralichthys olivaceus	enzyme expression is increased after treatment with polyinosinic:polycytidylic acid (5.99fold 0.05 mg/ml after 4 h), peptidoglycan from Staphylococcus aureus (5.36fold at 0.05 mg/ml after 2 h), and challenge with Edwardsiella tarda (3.1fold after 2 h). The enzyme is highly expressed in earlier embryonic development, and this pattern continues to the blastula stage and reaches the peak in the morula stage. Then, the enzyme expression decreases in subsequent stages, however, it increases again in the hatching stage	up

General Information

General Information	Comment	Organism
physiological function	the enzyme is involved in immune response and the activation of the nuclear factor-kappaB signaling pathways	Paralichthys olivaceus

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Release 2023.1 (January 2023)