Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme inhibition affects the binding of Hsp70 to RNA polymerase II, overview | Drosophila melanogaster |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA polymerase II C-terminal subunit | Drosophila melanogaster | Positive transcription elongation factor b is the major metazoan RNA polymerase II carboxyl-terminal domain Ser2 kinase, P-TEFb is critical for the maturation of RNA PolII into productive elongation in vivo, overview | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Kc cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA polymerase II C-terminal subunit | Positive transcription elongation factor b is the major metazoan RNA polymerase II carboxyl-terminal domain Ser2 kinase, P-TEFb is critical for the maturation of RNA PolII into productive elongation in vivo, overview | Drosophila melanogaster | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? | |
ATP + RNA polymerase II C-terminal subunit | phosphorylation of Ser2 | Drosophila melanogaster | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? |
Synonyms | Comment | Organism |
---|---|---|
P-TEFb | - |
Drosophila melanogaster |
Pol II CTD Ser2 kinase | - |
Drosophila melanogaster |
positive transcription elongation factor b | - |
Drosophila melanogaster |
RNA polymerase II carboxyl-terminal domain Ser2 kinase | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Drosophila melanogaster |