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Literature summary for 2.7.11.13 extracted from

  • Lee, Y.H.; Park, J.W.; Bae, Y.S.
    Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2 (2016), Biochimie, 121, 131-139.
    View publication on PubMed
Search for more literature for 2.7.11.13

Inhibitors

Inhibitors Comment Organism Structure
Goe6983
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein kinase CK2alpha Homo sapiens phosphorylation at serines 194 and 277 ADP + phosphorylated protein kinase CK2alpha
-
 ?
ATP + protein kinase CK2beta Homo sapiens phosphorylation at serine 148 ADP + phosphorylated protein kinase CK2beta
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HCT-116 cell
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + AAKIQASFRGHMARKK
-
 Homo sapiens ADP + AAKIQApSFRGHMARKK
-
 ?
ATP + protein kinase CK2alpha phosphorylation at serines 194 and 277 Homo sapiens ADP + phosphorylated protein kinase CK2alpha
-
 ?
ATP + protein kinase CK2beta phosphorylation at serine 148 Homo sapiens ADP + phosphorylated protein kinase CK2beta
-
 ?

Synonyms

Synonyms Comment Organism
PKCalpha isoform Homo sapiens
PKCbeta isoform Homo sapiens
PKCgamma isoform Homo sapiens
PKCtheta isoform Homo sapiens

General Information

General Information Comment Organism
metabolism overexpression of the enzyme isoforms: PKCalpha, PKCbeta, and PKCtheta, but not PKCgamma, stimulates protein kinase CK2 activity Homo sapiens