Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y223 | - |
- |
Homo sapiens | Q9Y223 | isoform 2; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, isoform GNE2 | - |
Homo sapiens | Q9Y223 | isoform 3; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, isoform GNE3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
colon | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + N-acetyl-D-mannosamine | - |
Homo sapiens | ADP + N-acetyl-D-mannosamine 6-phosphate | - |
? | |
additional information | isoform GNE2 displays an extended N-terminus compared with isoform GNE, which is linked directly to the epimerase domain. Recombinant GNE2 still possesses both enzymatic activities of GNE | Homo sapiens | ? | - |
? | |
additional information | isoform GNE3 displays an deleted N-terminus compared with isoform GNE. Recombinant GNE3 shows a total loss of the epimerase activity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GNE2 | enzyme isoform possessing extended N-terminus | Homo sapiens |
GNE3 | enzyme isoform possessing deleted N-terminus | Homo sapiens |
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | - |
Homo sapiens |